Eleonora Distrutti Selected Research

2- methyl- 3- (2- ((4- nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester

9/2004	Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice.
12/2003	NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Eleonora Distrutti Research Topics

Disease

32	Inflammation (Inflammations) 01/2022 - 01/2002
20	Colitis 01/2022 - 01/2002
10	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 11/2004
6	Fibrosis (Cirrhosis) 06/2020 - 02/2004
5	Fatty Liver 01/2022 - 01/2012
5	Cholestasis 01/2020 - 07/2007
4	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2018
4	Crohn Disease (Crohn's Disease) 01/2022 - 11/2009
4	Pruritus (Itching) 10/2021 - 12/2014
4	Insulin Resistance 10/2019 - 07/2007
4	Obesity 01/2019 - 01/2013
4	Liver Cirrhosis (Hepatic Cirrhosis) 01/2019 - 12/2003
4	Portal Hypertension 01/2016 - 12/2003
4	Pain (Aches) 01/2013 - 01/2006
3	Dysbiosis 01/2021 - 10/2019
3	Hepatitis 01/2020 - 11/2009
3	Disease Progression 01/2020 - 01/2018
3	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2020 - 12/2014
3	Weight Loss (Weight Reduction) 01/2019 - 11/2004
2	Vascular System Injuries 01/2022 - 10/2010
2	Liver Diseases (Liver Disease) 10/2021 - 01/2017
2	Stomach Neoplasms (Stomach Cancer) 01/2021 - 01/2016
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2020 - 09/2004
2	Body Weight (Weight, Body) 10/2019 - 01/2013
2	Neoplasms (Cancer) 01/2016 - 10/2007
2	Type 2 Diabetes Mellitus (MODY) 01/2015 - 07/2007
2	Rheumatoid Arthritis 12/2013 - 08/2011
2	Arthritis (Polyarthritis) 12/2013 - 08/2011
2	Dyslipidemias (Dyslipidemia) 01/2012 - 10/2010
2	Atherosclerosis 01/2012 - 10/2010
2	Hyperalgesia 05/2009 - 07/2006
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Vascular Diseases (Vascular Disease) 01/2022
1	Asthma (Bronchial Asthma) 01/2020
1	Chemical and Drug Induced Liver Injury 01/2020
1	Lung Diseases (Lung Disease) 01/2020

Drug/Important Bio-Agent (IBA)

21	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 11/2009
15	LigandsIBA 01/2022 - 07/2007
10	Messenger RNA (mRNA)IBA 01/2022 - 01/2002
7	LipidsIBA 01/2022 - 01/2012
6	CholesterolIBA 01/2022 - 02/2009
6	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2013 - 11/2009
5	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 10/2006 - 09/2005
4	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2013
4	Interleukin-6 (Interleukin 6)IBA 06/2020 - 01/2011
4	AcidsIBA 02/2019 - 10/2006
4	Sulfonic AcidsIBA 12/2017 - 01/2002
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2007 - 11/2002
3	obeticholic acidIBA 01/2020 - 12/2014
3	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 10/2019 - 12/2003
3	CytokinesIBA 02/2019 - 10/2011
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 12/2014
3	sym-trinitrobenzeneIBA 12/2017 - 01/2002
3	Dextran SulfateIBA 12/2017 - 11/2009
3	CollagenIBA 12/2013 - 12/2002
3	SteroidsIBA 01/2013 - 11/2002
3	Rifaximin (L 105)FDA Link 10/2011 - 01/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2009 - 01/2002
3	sodium bisulfide (NaHS)IBA 10/2006 - 09/2005
2	GTP-Binding Proteins (G-Protein)IBA 01/2022 - 01/2022
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 01/2022
2	oxidized low density lipoproteinIBA 10/2021 - 01/2019
2	pelargonidinIBA 01/2021 - 08/2019
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2021 - 08/2019
2	Interleukin-10 (Interleukin 10)IBA 06/2020 - 11/2002
2	isothiocyanic acidIBA 01/2020 - 01/2017
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 09/2004
2	Dextrans (Dextran)FDA Link 02/2019 - 01/2012
2	Insulin (Novolin)FDA Link 01/2019 - 01/2012
2	Alkaline PhosphataseIBA 01/2019 - 12/2014
2	Chenodeoxycholic Acid (Chenix)FDA Link 01/2019 - 10/2010
2	Drinking WaterIBA 12/2017 - 11/2009
2	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2017 - 11/2011
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2002
2	Integrin alpha1beta1IBA 01/2014 - 12/2002
2	Ritonavir (Norvir)FDA Link 01/2014 - 10/2010
2	Pregnane X ReceptorIBA 12/2013 - 10/2011
2	Chemokine CCL5IBA 12/2013 - 10/2011
2	ChemokinesIBA 12/2013 - 10/2011
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2013 - 04/2006
2	Analgesics (Analgesic Drugs)IBA 01/2013 - 06/2010
2	Apolipoproteins E (ApoE)IBA 01/2012 - 10/2010
2	Adenosine Triphosphate (ATP)IBA 10/2006 - 10/2006
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2006 - 09/2005
2	Interleukin-2 (IL2)IBA 11/2004 - 01/2002
2	2- methyl- 3- (2- ((4- nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid esterIBA 09/2004 - 12/2003
2	Prednisolone (Predate)FDA LinkGeneric 11/2002 - 01/2002
1	Atorvastatin (Lipitor)FDA Link 01/2022
1	Glucagon-Like Peptides (Enteroglucagon)IBA 01/2022
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2022
1	FlavonoidsIBA 01/2021
1	Bacterial AntigensIBA 06/2020
1	montelukast (Singulair)FDA Link 01/2020
1	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 01/2020
1	4-aminophenolIBA 01/2020
1	zafirlukast (Accolate)FDA LinkGeneric 01/2020
1	pranlukastIBA 01/2020

Therapy/Procedure

7	Therapeutics 01/2021 - 01/2013
2	Ligation 01/2020 - 02/2004
1	Liver Transplantation 01/2020